Hista-Biotic
Hista-Biotic is a low-histamine probiotic formulated to support gut microbiome balance without adding to a patient's histamine burden. Unlike general-purpose probiotics, every strain and subtype was selected specifically for histamine intolerance — not general gut health.
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Suggested use: 2 capsules per day, 30 minutes before meals. May be split into two doses. Keep refrigerated or store below 70°F once opened.
Ships via tracked courier within 5-7 business days. Flat-rate shipping is $9.99, free on orders over $250. We currently ship within the United States only.
Built to a clinical standard, not a supermarket one.
Scientifically Formulated
Every strain in Hista-Biotic is low-histamine or histamine-neutral — unlike most probiotics, which contain high-histamine strains that can trigger sensitive individuals.
Made in the USA, cGMP Certified
Manufactured in an FDA-registered, cGMP-compliant US facility, so you can stand behind quality and consistency when recommending it to patients.
Third-Party Tested, Every Batch
Independent lab verification on potency and purity for every production run — full Certificate of Analysis viewable below.
See the third-party test results for yourself.
We send every batch of Hista-Biotic to an independent lab for verification before it ships. Click the document to view the full report — CFU count, strain identity, and purity all confirmed by a party with no stake in the result.
- Verified CFU count at time of manufacture
- Strain identity confirmed by independent lab
- Every batch is tested to guarantee quality
How Hista-Biotic compares to a generic probiotic.
For a patient without histamine sensitivity, most probiotics are fine. For one who does, the strain selection is the whole ballgame.
Hista-Biotic may support those experiencing:
Histamine & Immune Response
Gut & Inflammatory
Neurological & Psychological
Chronic & Systemic
Real demand from real patients.
What customers are saying.
“A probiotic that actually helps with histamine response! I think it's also helping with reducing inflammation.”
“This product has been very helpful. I have not been able to take a probiotic because my system has not been able to tolerate it. But I am having positive results with this.”
“I've been taking it for about 4 months and I definitely notice when I don't take it for a few days. While I was waiting for a new shipment my histamine flares were quite noticeable in comparison to when I do take it.”
“Finally a probiotic I can take. After 3 weeks I started seeing fewer histamine issues.”
“I spent years pulling together whatever histamine-safe products happened to exist across other brands. Unitee exists so you don't have to.”
Common questions before stocking Hista-Biotic.
Most probiotics include strains that naturally produce histamine as part of fermentation. Hista-Biotic uses only strains and subtypes selected specifically for a low-histamine or histamine-neutral profile, so it doesn't add to a patient's existing histamine load.
The standard suggested use is 2 capsules daily, 30 minutes before a meal, which can be split into a morning and evening dose. Some patients tolerate it better starting with 1 capsule and titrating up.
Yes — Hista-Biotic is vegan and free from sugar, starch, artificial colors and flavors, corn, wheat, gluten, yeast, and dairy.
Yes, every batch is independently tested for potency and purity. The full Certificate of Analysis is viewable further up this page — just click it to zoom in.
Keep refrigerated after opening, or store in a cool, dry place below 70°F if refrigeration isn't available.
