DAO
DAO is a diamine oxidase enzyme supplement formulated to support efficient histamine breakdown and immune balance. Clinically studied and third-party tested, it's built to pair with low-histamine and gut-focused protocols for patients managing food-related histamine reactivity.
Apply Now
Suggested use: 2 capsules 15 minutes before meals containing histamine, or as directed by a healthcare practitioner. Store tightly sealed in a cool, dry place.
Ships via tracked courier within 5-7 business days. Flat-rate shipping is $9.99, free on orders over $250. We currently ship within the United States only.
Clinically studied enzymes, not a generic blend.
Clinically Relevant Potency
Formulated to deliver a clinically relevant level of active diamine oxidase, where many competing enzyme supplements carry a lower or inconsistent dose that undercuts real-world effectiveness.
Made in the USA, cGMP Certified
Manufactured in an FDA-registered, cGMP-compliant US facility, so you can stand behind quality and consistency when recommending it to patients.
Third-Party Tested, Every Batch
Independent lab verification on enzyme activity and purity for every production run — full Certificate of Analysis viewable below.
See the third-party test results for yourself.
We send every batch of DAO to an independent lab for verification before it ships. Click the document to view the full report — enzyme activity, purity, and potency all confirmed by a party with no stake in the result.
- Label claims verified against actual formulation
- Batch-specific results, not a one-time test
- Guaranteed quality in every bottle
How DAO compares to a generic enzyme supplement.
Not all DAO supplements deliver the same enzyme activity. Potency, sourcing, and testing are what separate a clinically useful dose from a label claim.
DAO may support those experiencing:
Histamine & Immune Response
Gut & Inflammatory
Neurological & Psychological
Chronic & Hormonal
Real demand from real patients.
What customers are saying.
“After taking DAO enzyme before meals, I feel much better and I have not felt the need to use an antihistamine product since. A great investment in myself, thank you!”
“For years I have struggled with eczema, set off by my high histamine. I take one capsule of DAO with each meal and all my rash has cleared up.”
“If you are someone struggling with histamine intolerance and food related symptoms, please try this product. Who knew that two capsules 15 minutes before a meal could make such a difference!”
“This has really been helping me feel more at ease about eating moderate to high histamine foods.”
“I spent years pulling together whatever histamine-safe products happened to exist across other brands. Unitee exists so you don't have to.”
Common questions before stocking DAO.
DAO is an enzyme responsible for degrading histamine in the digestive tract, such as that which is ingested through food. Hista-Biotic, on the other hand, supports the gut microbiome with low-histamine probiotic strains to promote the balance of internally-produced histamine. These two supplements target two different mechanisms which can act individually, or in combination for a broader histamine-support approach.
The standard suggested use is 2 capsules 15 minutes before meals containing histamine, or as directed by a healthcare practitioner.
Yes — DAO is gluten-free, non-GMO, and free from wheat, dairy, soy, yeast, sugar, hydrogenated oils, corn, and artificial colors or flavors.
Yes, every batch is independently tested for enzyme activity and purity. The full Certificate of Analysis is viewable further up this page — just click it to zoom in.
Store tightly sealed in a cool, dry place.
